Endocrine Abstracts

Insulin delivery through oral route requires protein protection against gastric environment followed by intestinal absorption. Several approaches using colloidal carriers have been proposed to achieve such attempts. Examples are nanoparticles produced from lipid materials (mono, di and triacylglycerols, waxes, fatty acids), polymeric materials (poly acid lactic/glycolic co-polymers, poly-epsilon caprolactone) or from polysaccharides (hyaluronic acid, dextran sulphate, alginate...